Main stars
- Sabrina Duncan - Kate Jackson - Private investigator for Townsend Associates - Seasons 1-3
- Jill Munroe - Farrah Fawcett-Majors - Private investigator for Townsend Associates - Season 1, recurring seasons 3-4
- Kelly Garrett - Jaclyn Smith - Private investigator for Townsend Associates - Seasons 1-5
- Kris Munroe - Cheryl Ladd - Private investigator for Townsend Associates - Seasons 2-5
- Tiffany Welles - Shelley Hack - Private investigator for Townsend Associates - Graduate from Boston police academy Season 4
- Julie Rogers - Tanya Roberts - Private investigator for Townsend Associates - Graduate from modeling school Season 5
- John Bosley - David Doyle - Private investigator, office manager for Townsend Associates - Seasons 1-5
- Charlie Townsend - John Forsythe - Owner of Townsend Associates (voice only) - Seasons 1-5
